Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores
Manuscript ID: 17836
| Submitting Author |
Sofer, Tamar
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|---|---|
| Submitting Author's Email | |
| Authors |
Yana Hrytsenko1,2,3,†, Benjamin Shea3†, Michael Elgart1,2, Nuzulul Kurniansyah1, Genevieve Lyons4, Alanna C. Morrison5, April P. Carson6, Bernhard Haring7,8, Braxton D. Mitchel9, Bruce M. Psaty10-13, Byron C. Jaeger14, C Charles Gu15, Charles Kooperberg16, Daniel Levy17, 18, Donald Lloyd-Jones19, Eunhee Choi20, Jennifer A Brody10,12, Jennifer A Smith21,22, Jerome I. Rotter23, Matthew Moll1,2,24, Myriam Fornage5,25, Noah Simon26, Peter Castaldi1,2, Ramon Casanova13, Ren-Hua Chung27, Robert Kaplan28,29, Ruth J.F. Loos30,31, Sharon L. R. Kardia20, Stephen S. Rich32, Susan Redline2,33, Tanika Kelly34, Timothy O’Connor8, Wei Zhao20,21, Wonji Kim35, Xiuqing Guo22, Yii Der Ida Chen22, the Trans-Omics in Precision Medicine Consortium, Tamar Sofer1,2,3,4,*
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| Journal name for most current submission |
Communications Biology
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| Associated TOPMed paper proposal | |
| This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI" |
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
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| Acknowledgments |
I have followed instructions for TOPMed Acknowledgments
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| I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones. |
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
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| I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable. |
Yes
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| I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented. |
Yes
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| I certify that all co-authors have reviewed and approved the manuscript for submission. |
Yes
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| Upload all necessary study-specific approval documentation. | |
| I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient. |
I have not
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| I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient. |
I have not
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| I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient. |
I have not
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TOPMed data used in this manuscript
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| Parent Study: Consent Group | Review Status |
|---|---|
| ARIC:DS-CVD-IRB | Approved automatically after 2 weeks |
| ARIC:HMB-IRB | Approved automatically after 2 weeks |
| Amish:HMB-IRB-MDS | Approved automatically after 2 weeks |
| BioMe:HMB-NPU | Approved |
| CARDIA:HMB-IRB | Approved automatically after 2 weeks |
| CARDIA:HMB-IRB-NPU | Approved automatically after 2 weeks |
| CFS:DS-HLBS-IRB-NPU | Approved automatically after 2 weeks |
| CHS:DS-CVD-MDS | Approved |
| CHS:DS-CVD-NPU-MDS | Approved |
| CHS:HMB-MDS | Approved |
| CHS:HMB-NPU-MDS | Approved |
| COPDGene:HMB | Approved |
| FHS:HMB-IRB-MDS | Approved |
| FHS:HMB-IRB-NPU-MDS | Approved |
| GENOA:DS-ASC-RF-NPU | Approved |
| GenSalt:DS-HCR-IRB | Approved automatically after 2 weeks |
| HCHS_SOL:HMB | Approved automatically after 2 weeks |
| HCHS_SOL:HMB-NPU | Approved automatically after 2 weeks |
| JHS:DS-FDO-IRB | Approved |
| JHS:DS-FDO-IRB-NPU | Approved |
| JHS:HMB-IRB | Approved |
| JHS:HMB-IRB-NPU | Approved |
| MESA:HMB | Approved |
| MESA:HMB-NPU | Approved |
| Partners:HMB | Request cancelled by original requester |
| THRV:DS-CVD-IRB-COL-NPU-RD | Approved automatically after 2 weeks |
| WHI:HMB-IRB | Approved |
| WHI:HMB-IRB-NPU | Approved |
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