Carriers of rare damaging CCR2 genetic variants are at lower risk of atherosclerotic disease

Marios K. Georgakis, MD, PhD*1-3, Rainer Malik, PhD*1, Natalie R. Hasbani, MPH4, Gabrielle Shakt5,6, Alanna C. Morrison, PhD4, BS, Noah L. Tsao, BS5,6, Renae Judy, MS5,6, Braxton D. Mitchell, PhD7,8, Huichun Xu, MD, PhD7, May E. Montasser, PhD7, Ron Do, PhD9,10, Eimear E. Kenny9,11-13, Ruth J.F. Loos, PhD9, James G. Terry, MS14, John Jeffrey Carr, MD14, Myriam Fornage, PhD4,15, Joshua C. Bis, PhD16, Bruce M. Psaty, MD, PhD16-18, W. T. Longstreth, MD, MPH18,19, Kendra A Young, MSPH, PhD20, Sharon M Lutz, PhD21,22, Michael H Cho, MD, MPH23, Jai Broome, BA24, Alyna T. Khan24, Fei Fei Wang, BS24, Nancy Heard-Costa, PhD25,26, Sudha Seshadri, MD27, Ramachandran S. Vasan, MD25,26,28, Nicholette D. Palmer, PhD29, Barry I. Freedman, MD30, Donald W. Bowden, PhD29, Lisa R. Yanek, MPH31, Brian G. Kral, MD, MPH31, Lewis C. Becker, MD31, Patricia A. Peyser, PhD32, Lawrence F. Bielak, DDS, MPH32, Farah Ammous, PhD32, April P. Carson, PhD, MSPH33, Michael E. Hall, MS, MS33, Laura M. Raffield, PhD34, Stephen S. Rich, PhD35, Wendy S. Post, MD36, Russel P. Tracy, PhD37, Kent D. Taylor, PhD38, Xiuqing Guo, PhD38, Michael C. Mahaney, PhD39, Joanne E. Curran, PhD39, John Blangero, PhD39, Shoa L. Clarke, MD, PhD40-42, Jeffrey W. Haessler, MS43, Yao Hu, PhD43, Themistocles L. Assimes, MS, PhD40-42, Charles Kooperberg, PhD43, Scott M. Damrauer, MD5,6,44, Jerome I. Rotter, MD39, Paul S. de Vries, PhD4, Martin Dichgans, MD1,3,45