Skip to main content

Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits

Submitting Author
Patel, Roshni
Submitting Author's Email
rpatel7@stanford.edu
Authors
Roshni A. Patel*,
Shaila A. Musharoff*,
Jeffrey P. Spence,
Harold Pimentel,
Catherine Tcheandjieu,
Hakhamanesh Mostafavi,
Nasa Sinnott-Armstrong,
Shoa L. Clarke,
Courtney J. Smith,
VA Million Veteran Program,
Peter P. Durda,
Kent D. Taylor,
Russell Tracy,
Yongmei Liu,
Craig W. Johnson,
Francois Aguet,
Kristin G. Ardlie,
Stacey Gabriel,
Josh Smith,
Deborah A. Nickerson,
Stephen S. Rich,
Jerome I. Rotter,
Philip S. Tsao,
Themistocles L. Assimes,
Jonathan K. Pritchard
Journal name for most current submission
American Journal of Human Genetics
Associated TOPMed paper proposal
Investigating cross-population portability of variant effect sizes
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable.
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented.
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission.
Yes
Upload all necessary study-specific approval documentation.
MESA_approval.pdf
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.

TOPMed data used in this manuscript

The data set approvals listed here should match the TOPMed data used in this manuscript.

Don't see all the data sets you need? Request more data sets at any time.

Please "cancel" any data set requests that were not used in this manuscript. Note: only the paper proposal submitter or their designated updater can cancel data sets.

Parent Study: Consent Group Review Status
MESA:HMB Approved
MESA:HMB-NPU Approved