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Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

Submitting Author
Sofer, Tamar
Submitting Author's Email
tsofer@bwh.harvard.edu
Authors
Tamar Sofer, Xiuwen Zheng, Cecelia A. Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P Conomos, Joshua Bis, Timothy A. Thornton, Adam Szpiro, Jeffrey R. O’Connell, Ethan M. Lange, Yan Gao, L. Adrienne Cupples, Bruce M. Psaty, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Kenneth M. Rice
Journal name for most current submission
Nature Communications
Associated TOPMed paper proposal
Effects of non-constant variance on association tests using linear regression
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable.
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented.
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission.
Yes
Upload all necessary study-specific approval documentation.
Approval from JHS publication committee
Evidence that I have sent an email to Amish study with the manuscript
Evidence that I sent an email to the Broad
Evidence that I sent an email to FHS/NHLBI
Evidence that I sent an email to the IRC
Evidence that I have sent an email to the UW sequencing center
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.

TOPMed data used in this manuscript

The data set approvals listed here should match the TOPMed data used in this manuscript.

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Parent Study: Consent Group Review Status
Amish:HMB-IRB-MDS Approved automatically after 2 weeks
CFS:DS-HLBS-IRB-NPU Approved automatically after 2 weeks
COPDGene:DS-CS-RD Disapproved
COPDGene:HMB Approved
CRA:DS-ASTHMA-IRB-MDS-RD Approved
EOCOPD:DS-CS-RD Disapproved
FHS:HMB-IRB-MDS Approved automatically after 2 weeks
FHS:HMB-IRB-NPU-MDS Approved automatically after 2 weeks
GALAII:DS-LD-IRB-COL Disapproved
JHS:DS-FDO-IRB Approved
JHS:DS-FDO-IRB-NPU Approved
JHS:HMB-IRB Approved
JHS:HMB-IRB-NPU Approved
MGH_AF:DS-AF-IRB-RD Approved automatically after 2 weeks
MGH_AF:HMB-IRB Approved automatically after 2 weeks
SAGE:DS-LD-IRB-COL Disapproved
Samoan:GRU-IRB-PUB-COL-NPU-GSO Approved