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Rare variant enriched identity-by-descent enables the detection of distant relatedness and older divergence between populations

Submitting Author
Shetty, Amol
Submitting Author's Email
ashetty@som.umaryland.edu
Authors
Amol C. Shetty, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Population Genetics Working Group, Jeffrey O’Connell, Braxton D. Mitchell, Timothy D. O’Connor
Journal name for most current submission
Bioinformatics
Associated TOPMed paper proposal
Rare variant enriched IBD to detect distant relatedness within and between cohorts
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable.
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented.
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission.
Yes
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I have not
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I have not
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I have not

TOPMed data used in this manuscript

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Parent Study: Consent Group Review Status
Amish:HMB-IRB-MDS Approved