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Multivariate adaptive shrinkage improves cross-population transcriptome prediction and association studies in underrepresented populations

Submitting Author
Wheeler, Heather
Submitting Author's Email
hwheeler1@luc.edu
Authors
Daniel S. Araujo1, Chris Nguyen2, Xiaowei Hu3, Anna V. Mikhaylova4, Chris Gignoux5, Kristin Ardlie6, Kent D. Taylor7, Peter Durda8, Yongmei Liu9, George Papanicolaou10, Michael H. Cho11, Stephen S. Rich3, Jerome I. Rotter7, NHLBI TOPMed Consortium, Hae Kyung Im12, Ani Manichaikul3, Heather E. Wheeler1,2,*
Journal name for most current submission
HGG Advances
Associated TOPMed paper proposal
Cross-population and cross-cell type prediction of RNA using TOPMed MESA Multi-omics data
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
This manuscript has been approved by the original paper proposal's Working Group(s) or is "single PI"
Acknowledgments
I have followed instructions for TOPMed Acknowledgments
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I've received approval for all data sets used in this manuscript, including adding new data sets and canceling all unused ones.
I have followed the Data Use Limitations for each of the data sets used in this manuscript, if applicable.
Yes
I've included at least 1 co-author from each study used in analysis or the PI declined an offer to have their study represented.
Yes
I certify that all co-authors have reviewed and approved the manuscript for submission.
Yes
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 DCC/ACC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I’ve included at least 1 IRC author, or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.
I've included at least 1 author from relevant omics center(s) or they declined authorship or deemed acknowledgement sufficient.

TOPMed data used in this manuscript

The data set approvals listed here should match the TOPMed data used in this manuscript.

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Parent Study: Consent Group Review Status
MESA:HMB Approved
MESA:HMB-NPU Approved